See also: [[Sepsis]] See: [OpenEvidence CRP conversation](https://www.openevidence.com/ask/63d120ef-d75b-4c19-b88a-d3f366d83c84) - [How do bacteraemic patients present to the emergency department and what is the diagnostic validity of the clinical parameters — temp, CRP, SIRS?](https://pmc.ncbi.nlm.nih.gov/articles/PMC4107625/) - CRP >100 PPV for bacteraemia of 11.8% and NPV 98.3% - [C-reactive protein as a prognostic factor in intensive care admissions for sepsis: A Swedish multicenter study](https://pubmed.ncbi.nlm.nih.gov/31855709/) - An admission CRP level >100 mg/L is associated with an increased risk of ICU and 30-day mortality as well as prolonged LOS in survivors, irrespective of morbidity measured with SAPS-3. Thus, CRP may be a simple, early marker for prognosis in ICU admissions for sepsis. - [Diagnostic and prognostic significance of serum C-reactive protein levels in patients admitted to the department of medicine](https://pubmed.ncbi.nlm.nih.gov/19365169/) - Very high CRP >200 mg/L was a marker of sepsis. In contrast, low CRP range (<10 mg/L) was characteristic to cardiovascular diseases and viral infections, but included none of the patients with severe infections or sepsis. Furthermore, higher CRP was significantly associated with mortality, the need for intubation, and longer hospitalization, and had better distinguishing ability compared with erythrocyte sedimentation rate or platelets count for the comparison of major disease categories, such as bacterial infections, inflammatory and rheumatic disease, viral infections, and cardiovascular disorders.