see: [hayes' Buprenorphine](x-devonthink-item://0332E806-B76E-4148-8BA7-7B3C140A2714), [Austin Buprenorphine OD](x-devonthink-item://FC9CB0F8-AFCD-4EC8-AD11-5A9F4D9C1B12) Suboxone = buprenorphine + naloxone note that suboxone lowest dose is 10x higher than a 200mcg temgesic **preparations** | brand name | dose | | ------------------- | ------------------------------- | | suboxone s/L tablet | 2mg / 0.5mg<br>8mg/2mg | | suboxone s/l film | 4mg/1mg<br>12mg/4mg | | norspan 5 | 5mcg/hour (total content = 5mg) | | temgesic | 200 mcg | # dosage for opiate withdrawal - suboxone s/l 2-8 mg depending on severity of withdrawl symptoms, in 1 or two doses on the first day - increase daily dose by 2-8mg every 1-4 days depending on withdrawl sx - usual maintenance range is 12-24 mg daily - max per day is 32mg/day # precipitated withdrawl - if started too soon after a dose of an opioid, buprenorphine may precipitate withdrawl symptoms because it is a partial agonist and acts as a relative antagonist