see also: [[Hypertensive Emergency]], [[haemorrhagic stroke]], [[Urapidil]] see: [Nicardipine RMH guideline](x-devonthink-item://1B89128C-3783-4379-A8EA-1E7C7DC8587E) > [!info] > [Category::anti-hypertensive] > [Class::calcium channel blocker] - useful for [[Hypertensive Emergency#hypertensive encephalopathy]] and basal ganglia stroke / hypertensive stroke > - **Onset:** 1 min > - **Peak:** 10 min > - **Duration:** 3H **Key issues:** - *contraindicated* in patients with Aortic stenosis # Dose - 5mg/ hour IV - titrate in 2.5mg/h increments Q5-15 min based on BP response to max infusion rate of 15mg/H Aim to reduce bp by 10-20% per hour