see also: #paeds > [!info] > Category: `=this.Category` > - xanthine derivative - Competitive phosphodiasterase inhibitor → increase cAMP, inhibit leukotriene synthesis → reduce inflammation and innate immunity, smooth muscle relaxation - Nonselective adenosine receptor antagonist → explains cardiac effects **Onset:** **half-life:** **Key issues:** # effects # uses - COPD - [[Asthma]] third line!! - Infant aponea - Experimental: treat [[Heart Block|AV nodal block]] (eg post MI or post COVID rare cases) # Dose