See: [Milk borne diseases](https://en.wikipedia.org/wiki/Milk_borne_diseases) - [cubox](cubox://highlight?id=7345801532371110314), [Raw milk - bear](bear://x-callback-url/open-note?id=F27D4DCE-34FA-4E51-B1CC-8B72973DD803-9486-000005353D9691DD)
Listeriosis primarily affects:
- Immunocompromised individuals (e.g. those with leukemia, diabetes, or cancer)
- Elderly patients
- Pregnant women and their fetuses
- Newborn infants
- Individuals on immunosuppressive therapies (e.g. corticosteroids)
In healthy, nonpregnant adults, listeria infection is rare and typically limited to mild, self-limiting, flu-like symptoms or febrile gastroenteritis following ingestion of contaminated food.
In immunosuppressed, nonpregnant adults, listeriosis may present more severely as:
- Acute meningoencephalitis
- Brain abscess
- Bacteraemia
Other possible manifestations include:
- Pneumonia
- Endocarditis
- Infected prosthetic joints
- Localised internal abscesses eg liver, other organs
Presentation may be acute or subacute, with approximately 60% of cases developing symptoms more than 24 hours after exposure.
Notably, the **incubation** period for listeriosis can be **up to 70 days**, so continued vigilance is required for several weeks following exposure.
Common symptoms include:
- Fever
- Severe headache
- Nausea and vomiting
These may progress to prostration and shock in severe cases.