see also: [[neonatal jaundice]], [[Anti-D]], [[Coombs test]] #paeds #ob-gyn > [!summary] > > **treatment**:: [[Anti-D]] # Erythroblastosis fetalis - extramedullary haematopoesis → high levels of nucleated red cells - haemolysis → ↑ bilirubin (neurotoxic, but should be removed by placenta) - cardiac failure - oedema - ascites - pericardial effusion - disturbed liver function # ABO haemolytic disease - milder than isoimmunisation by Rh and other antigens - 25% of pregnancies have potential maternal-infant ABo incompatibility - <10% have any problems - almost always ==group A or B infants of group O mothers== - neonatal direct Coombs' test may be positive or negative **features** - serious fetal effects rare - **early [[neonatal jaundice]] <24 hours requiring phototherapy in 10%** - kernicterus almost never occurs