See also [[Blood gas#2. oxygenation (A-a gradient)|a-a gradient]] ![[Pasted image 20240512211059.jpg]] Relationship between paO2 and SaO2 Implications: - upper flat part means that if the pO2 alveolar gass falls, loading of O2 is not substantially affected  - lower steep part meas that peripheral tissue can draw large amount of O2 for only a small drop in capillary pO2  CADET face right: increased CO2, acidosis, increased 2-3 DPG, exercise, and increased temperature shift the curve to the right