> - **risk_dose**:: 10mcg/kg > - triad of drowsiness, [[miosis]], and bradycardia can mimic opiate  \> 10 mcg/kg associated with significant tox ; bradycardia and hypotension \> 20 mcg/kg a/w resp depression or aponea **1-2 tablets potentially life threatening in kids!** rapid onset, tox can last 24 hours Drowsy, ataxia, miosis, coma bradycardia, hypotensive, AV block aponea  **Treatment**  - supportive - don't give charcoal due to rapid drowsiness - naloxone not routine -- can consider 100mcg Q1 min up to 400mcg