See also [[Venlafaxine]] - Deliberate self-poisioning with the selective serotonin reuptake inhibitors (SSRIs) is common and usually follows a benign course. Serotonin toxicity develops in a small minority. - Severe [[Serotonin Syndrome]] does not develop unless there is co-ingestion of other serotonergically active drugs. - Mild serotonin syndrome occurs in less than 20% and manifests as anixety, tremor, tachycardia, bradycardia and mydriasis. - Seizures are uncommon and mostly associated with Citalopram (around 2%) and usually heralded by increased anxiety, sweating, tremor, tachycardia and mydriasis. Short lived and easily controlled with benzodiazepines. - [[Venlafaxine]] does have dose dependent risk of delayed onset seizures >5g - QT prolongation occurs after citalopram and escitalopram overdose and is dose-dependent.