See also: [[Hydrocarbons]], [[Essential oils]], [[toxic alcohols]], [[Hydrofluoric Acid]], [[Methemoglobinemia]], [[Toluene toxicity]] See: [Hayes’ - Solvent Abuse](x-devonthink-item://7218E349-C347-4E7D-B839-C9B2EDC1C6F8), [Rosen’s - Hydrocarbons](x-devonthink-item://B095C1E6-4BB9-40C0-B8CD-D2D14C1874BD), [Murray’s - solvent abuse](x-devonthink-item://DA1896AC-D57C-4A67-B2C7-65B1D27BB53E?page=88), [RCH - inhalants volatile substance abuse, chroming](https://www.rch.org.au/clinicalguide/guideline_index/inhalants_volatile_substance_use/) > not much in this note because essentially most solvents are either hydrocarbons or essential oils management - Mostly seen with inhalational abuse - [[Toluene toxicity]] deserves a special mention because it is occasionally used for huffing / chroming - May need workup for [[Delirium vs psychosis|delirium]] - Treat [[Seizures]] PRN - supportive care for acid/base, cardiac disturbances The organic solvents are all volatile liquids and well absorbed via the inhalational route. Peak blood concentrations are achieved within 15–30 minutes of inhalation. These agents are highly lipid soluble and following absorption are preferentially distributed to lipid-rich organs notably the CNS and liver. After inhalation stops, excretion by the lungs takes place. Solvents are also metabolised by the liver with elimination half-lives in the order of 15–72 hours